Scrum-half Robson, whose Challenge Cup triumph came with Gloucester Rugby in the 2014/15 season, forms a halfback partnership with Jacob Umaga in a much-changed Wasps starting XV that beat Sale Sharks in the Premiership Rugby Cup last weekend.

Wing Josh Bassett is added to the back three, whereas Jimmy Gopperth and Malakai Fekitoa both return to the centres.

In the forwards, Gabriel Oghre comes into the front row as captain Joe Launchbury starts in the second row with Alfie Barbeary lining up at No.8.

Visitors Newcastle, who are third in Pool A, head to the Coventry Building Society Arena with Tom Penny, Adam Radwan and Mateo Carreras all returning to form their back three.

George Wacokecoke starts in midfield and Will Haydon-Wood comes in to form a halfback partnership with Louis Schreuder.

George McGuigan and Trevor Davison start in the front row as Greg Peterson and Sean Robinson make up the second row with Will Welch returning at blindside.

Elsewhere in the Premiership, London Irish welcome fellow EPCR Challenge Cup side Northampton Saints to the Brentford Community Stadium as Saracens host Bristol Bears and Bath Rugby take on Sale Sharks.

In the United Rugby Championship, Cardiff Rugby host Glasgow Warriors in an all-EPCR Challenge Cup encounter as Zebre Parma take on Scarlets and Edinburgh Rugby head to Sharks.

In the TOP 14, there are two all-EPCR Challenge Cup clashes as CA Brive face Castres Olympique and Section Paloise host USAP. Biarritz Olympique travel to Montpellier Hérault Rugby and RC Toulon entertain ASM Clermont Auvergne.

On Sunday, EPCR Challenge Cup contenders Lyon head to Stade Toulousain in the TOP 14.

Challenge Cup winner Dan Robson is set to make his 150th appearance for Wasps on Saturday as Lee Blackett’s men face Newcastle Falcons in an all-EPCR Challenge Cup clash in the Gallagher Premiership.